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KIT Ligand Protein (KITLG) (AA 26-189)

This Recombinant KIT Ligand protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN667064

Quick Overview for KIT Ligand Protein (KITLG) (AA 26-189) (ABIN667064)

Target

See all KIT Ligand (KITLG) Proteins
KIT Ligand (KITLG)

Protein Type

Recombinant

Origin

  • 25
  • 17
  • 13
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Mouse

Source

  • 32
  • 8
  • 8
  • 6
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Application

SDS-PAGE (SDS)

Purity

> 95 %
  • Protein Characteristics

    AA 26-189

    Sequence

    MKEICGNPVT DNVKDITKLV ANLPNDYMIT LNYVAGMDVL PSHCWLRDMV IQLSLSLTTL LDKFSNISEG LSNYSIIDKL GKIVDDLVLC MEENAPKNIK ESPKRPETRS FTPEEFFSIF NRSIDAFKDF MVASDTSDCV LSSTLGPEKD SRVSVTKPFM LPPVA

    Characteristics

    mouse SCF, 26-189 aa, mouse, Recombinant, E.coli

    Purification

    > 95% by SDS-PAGE
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  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Phosphate-Buffered Saline ( pH 7.4) containing 10 % glycerol

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
  • Target

    KIT Ligand (KITLG)

    Alternative Name

    c-kit Ligand/SCF

    Background

    Stem Cell Factor (SCF) is a glycoprotein that plays a key role in hematopoiesis acting both as a positive and negative regulator, often in synergy with other cytokines. SCF binds to and activates the SCF receptor (SCFR), a receptor tyrosine kinase. SCF stimulates the proliferation of mast cells and is able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. It also mediates cellcell adhesion and acts synergistically with other cytokine. Recombinant mouse SCF was expressed in E. coli and purified by conventional column chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer

    Molecular Weight

    18.4 kDa (165aa) confirmed by MALDI-TOF

    NCBI Accession

    NP_038626

    Pathways

    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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